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It supports the normal growth and function of lymphocytes like the T-cells and B-cells, important for recognizing and fighting infection

Therefore, overcoming tamoxifen-induced activation of the ARE could increase the efficacy of tamoxifen in treating breast cancer

The countries/territories with the highest number of publications and potential biomarkers evaluated were Brazil, with 23 studies and 78 biomarkers

* Correspondence: Hongying Kuang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers